This is a series.
Inspired by ancient Peruvian culture and set in an Incan empire, The Emperor's New Groove follows Emperor Kuzco (Spade), who is accidentally transformed into a llama by his treacherous ex-advisor, Yzma (Kitt), and her dimwitted henchman Kronk (Warburton) in a botched attempt to kill him by poisoning his drink. For the emperor to change back into a human, he entrusts a village leader, Pacha (Goodman), to escort him back to the palace before Yzma can track them down and finish him off.